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Chemical Structure : AC1-IN-38
CAS No.: 2762422-55-7
Catalog No.: PC-72951Not For Human Use, Lab Use Only.
AC1-IN-38 is a potent, selective inhibitor of adenylyl cyclase type 1 (AC1) with IC50 of 0.54 uM.
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|---|---|---|---|
| 5 mg | $328 | In stock | |
| 10 mg | $528 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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AC1-IN-38 is a potent, selective inhibitor of adenylyl cyclase type 1 (AC1) with IC50 of 0.54 uM.
AC1-IN-38 shows selectivity over a closely related isoform AC8, and no activity against AC2/5 and other common neurological targets.
AC1-IN-38 displayed modest antiallodynic effects in a mouse model of inflammatory pain.
| M.Wt | 355.373 | |
| Formula | C18H18FN5O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-(1-(4-ethyl-6-oxo-1,6-dihydropyrimidin-2-yl)-3-methyl-1H-pyrazol-5-yl)-2-fluoro-5-methylbenzamide |
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1. Jason A. Scott, et al. Journal of Medicinal Chemistry. DOI: 10.1021/acs.jmedchem.1c01759
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