Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Nuclear Receptor/Transcription Factor-RAR/RXR-AC261066
AC261066

Chemical Structure : AC261066

CAS No.: 870773-76-5

Add to Favorites

AC261066 (AC-261066;AC261)

Catalog No.: PC-35516Not For Human Use, Lab Use Only.

AC261066 (AC-261066, AC261) is a potent, selective, orally available RARβ2 agonist with pEC50 of 8.1, displays selectivity over RARβ1, RARα and RARγ (pEC50=6.4, 6.2 and 6.3).

Packing Price Stock Quantity
10 mg $188 In stock
25 mg $328 In stock
50 mg Get quote
100 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

AC261066 (AC-261066, AC261) is a potent, selective, orally available RARβ2 agonist with pEC50 of 8.1, displays selectivity over RARβ1, RARα and RARγ (pEC50=6.4, 6.2 and 6.3).
AC261066 exerts cardioprotective effects, also exhibits therapeutic effects in high fat diet (HFD) model of diabetic nephropathy (DN).

Physicochemical Properties

M.Wt 353.408
Formula C17H20FNO4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-[4-(2-Butoxyethoxy-)-5-methyl-2-thiazolyl]-2-fluorobenzoic acid

References

1. Lund BW, et al. J Med Chem. 2005 Dec 1;48(24):7517-9.

2. Trasino SE, et al. Diabetes Obes Metab. 2016 Feb;18(2):142-51.

3. Trasino SE, et al. J Mol Med (Berl). 2016 Oct;94(10):1143-1151.

4. Marino A, et al. J Pharmacol Exp Ther. 2018 Aug;366(2):314-321.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: