Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : AC261066
CAS No.: 870773-76-5
Catalog No.: PC-35516Not For Human Use, Lab Use Only.
AC261066 (AC-261066, AC261) is a potent, selective, orally available RARβ2 agonist with pEC50 of 8.1, displays selectivity over RARβ1, RARα and RARγ (pEC50=6.4, 6.2 and 6.3).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $188 | In stock | |
| 25 mg | $328 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
AC261066 (AC-261066, AC261) is a potent, selective, orally available RARβ2 agonist with pEC50 of 8.1, displays selectivity over RARβ1, RARα and RARγ (pEC50=6.4, 6.2 and 6.3).
AC261066 exerts cardioprotective effects, also exhibits therapeutic effects in high fat diet (HFD) model of diabetic nephropathy (DN).
| M.Wt | 353.408 | |
| Formula | C17H20FNO4S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
4-[4-(2-Butoxyethoxy-)-5-methyl-2-thiazolyl]-2-fluorobenzoic acid |
|
1. Lund BW, et al. J Med Chem. 2005 Dec 1;48(24):7517-9.
2. Trasino SE, et al. Diabetes Obes Metab. 2016 Feb;18(2):142-51.
3. Trasino SE, et al. J Mol Med (Berl). 2016 Oct;94(10):1143-1151.
4. Marino A, et al. J Pharmacol Exp Ther. 2018 Aug;366(2):314-321.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
