ACG-416B | ChoKα inhibitor | Probechem Biochemicals

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Chemical Structure : ACG-416B

ACG-416B (ACG416B)

Catalog No.: PC-60877Not For Human Use, Lab Use Only.

ACG-416B (ACG416B) is a potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 0.13 uM, >385-fold selectivity over ChoKβ.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

ACG-416B (ACG416B) is a potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 0.13 uM, >385-fold selectivity over ChoKβ.
ACG-416B demonstrates in vitro antiproliferative activity against HT29 cells with IC50 of 1.94 uM.

Physicochemical Properties

M.Wt	708.542
Formula	C38H36Br2N4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1,1'-([1,1'-biphenyl]-3,3'-diylbis(methylene))bis(4-(methyl(phenyl)amino)pyridin-1-ium) bromide

References

1. Lacal JC, et al. Mol Cancer Ther. 2015 Jan;14(1):31-9.

2. Patent US 20110178124 A1. Pyridinium and quinolinium derivatives.

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ACG-416B (ACG416B)

Biological Activity

Physicochemical Properties

References

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