| Cat. No. |
Product Name |
Information |
| PC-35395 |
EB-3D
ChoKα inhibitor
|
EB-3D is a novel potent and selective choline kinase ChoKα inhibitor with IC50 of 1.0 uM (purified ChoKα1), strongly impairs cell proliferation in a variety of different cancer cell lines. |
| PC-61516 |
ChoKα inhibitor CK37
ChoKα inhibitor
|
ChoKα inhibitor CK37 is a potent, specific, competitive inhibitor of choline kinase-α (Chok-α) by targeting the choline binding site. |
| PC-60876 |
JCR795b
Choline kinase inhibitor
|
JCR795b is a competitive, small molecule inhibitor of choline kinase (ChoK) with in vitro IC50 of 3.5 uM. |
| PC-60877 |
ACG-416B
ChoKα inhibitor
|
ACG-416B (ACG416B) is a potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 0.13 uM, >385-fold selectivity over ChoKβ. |
| PC-60878 |
ACG-548B
ChoKα inhibitor
|
ACG-548B is a potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 0.12 uM, >400-fold selectivity over ChoKβ. |
| PC-60867 |
Hemicholinium-3
Choline kinase inhibitor
|
Hemicholinium-3 (HC-3) is a competitive, small molecule inhibitor of choline kinase (ChoK) with ex vivo IC50 of 500 uM, also bolcks the sodium and chloride-dependent transport system and affects choline acetyltransferase. |
| PC-60866 |
MN58b
ChoKα inhibitor
|
MN58b is a potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 1.4 uM, >30-fold selectivity over ChoKβ and does not affect MAPKs, PI3Ks, and other enzymes involved in the regulation of phospholipid metabolism. |
| PC-60865 |
JAS239
Choline kinase inhibitor
|
JAS239 is a carbocyanine dye that binds and competitively inhibits choline kinase (ChoK) intracellularly, prevents choline phosphorylation and induces cell death in breast cancer cell lines. |
| PC-60864 |
RSM-932A
ChoKα inhibitor
|
RSM-932A (TCD-717) is a potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 1.0 uM, 33-fold selectivity over ChoKβ. |
| PC-60863 |
V-11-0711
ChoKα inhibitor
|
V-11-0711 (V-11 0711) is a novel potent and selective choline kinase alpha (ChoKα) inhibitor with IC50 of 20 nM, with 11 fold less activity against ChoKβ. |
