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Hemicholinium-3

Chemical Structure : Hemicholinium-3

CAS No.: 312-45-8

Hemicholinium-3 (HC-3, Hemicholinium3)

Catalog No.: PC-60867Not For Human Use, Lab Use Only.

Hemicholinium-3 (HC-3) is a competitive, small molecule inhibitor of choline kinase (ChoK) with ex vivo IC50 of 500 uM, also bolcks the sodium and chloride-dependent transport system and affects choline acetyltransferase.

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Biological Activity

Hemicholinium-3 (HC-3) is a competitive, small molecule inhibitor of choline kinase (ChoK) with ex vivo IC50 of 500 uM, also bolcks the sodium and chloride-dependent transport system and affects choline acetyltransferase.

Physicochemical Properties

M.Wt 574.35
Formula C24H34Br2N2O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2,2'-([1,1'-Biphenyl]-4,4'-diyl)bis(2-hydroxy-4,4-dimethylmorpholin-4-ium) bromide

References

1. Hernández-Alcoceba R, et al. Oncogene. 1997 Nov 6;15(19):2289-301.

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