Chemical Structure : ACG-548B
CAS No.: 795316-16-4
Catalog No.: PC-60878Not For Human Use, Lab Use Only.
ACG-548B is a potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 0.12 uM, >400-fold selectivity over ChoKβ.
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ACG-548B is a potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 0.12 uM, >400-fold selectivity over ChoKβ.
ACG-548B demonstrates in vitro antiproliferative activity against HT29 cells with IC50 of 2.08 uM.
M.Wt | 777.426 | |
Formula | C38H34Br2Cl2N4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
1,1'-([1,1'-biphenyl]-3,3'-diylbis(methylene))bis(4-((4-chlorophenyl)(methyl)amino)pyridin-1-ium) bromide |
1. Lacal JC, et al. Mol Cancer Ther. 2015 Jan;14(1):31-9.
2. Patent US 20110178124 A1. Pyridinium and quinolinium derivatives.
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