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RSM-932A

Chemical Structure : RSM-932A

CAS No.: 850807-63-5

RSM-932A (TCD-717, TCD717, RSM932A)

Catalog No.: PC-60864Not For Human Use, Lab Use Only.

RSM-932A (TCD-717) is a potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 1.0 uM, 33-fold selectivity over ChoKβ.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

RSM-932A (TCD-717) is a potent, selective choline kinase α (ChoKα) inhibitor with IC50 of 1.0 uM, 33-fold selectivity over ChoKβ.
RSM-932A demonstrates potent in vitro antiproliferative (HT29 IC50=1.15 uM) and in vivo antitumoral activity against human xenografts in mice with low toxicity profiles.

Physicochemical Properties

M.Wt 717.737
Formula C46H38Cl2N42Br
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Quinolinium, 1,1'-[[1,1'-biphenyl]-4,4'-diylbis(methylene)]bis[4-[(4-chlorophenyl)methylamino]-, dibromide (9CI)

References

1. Lacal JC, et al. Mol Cancer Ther. 2015 Jan;14(1):31-9.

2. Zimmerman T, et al. Antimicrob Agents Chemother. 2013 Dec;57(12):5878-88.

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