Chemical Structure : ACT-541468
CAS No.:
1505484-82-1
ACT-541468
(Nemorexant;ACT541468;DORA)
Catalog No. : PC-60727Not For Human Use, Lab Use Only.
ACT-541468 (Nemorexant) is a potent, selective, dual orexin receptor 1 and 2 (OX1 and OX2) antagonist with Kb of 0.52 and 0.78 nM, respectively.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6072701
Biological Activity
ACT-541468 (Nemorexant) is a potent, selective, dual orexin receptor 1 and 2 (OX1 and OX2) antagonist with Kb of 0.52 and 0.78 nM, respectively.
Physicochemical Properties
M.Wt
450.927
Formula
C23H23ClN6O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(S)-(2-(5-chloro-4-methyl-1H-benzo[d]imidazol-2-yl)-2-methylpyrrolidin-1-yl)(5-methoxy-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone
References
1. Treiber A, et al. J Pharmacol Exp Ther.
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