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Chemical Structure : ACT-777991
CAS No.: 1967811-46-6
Catalog No.: PC-20096Not For Human Use, Lab Use Only.
ACT-777991 (ACT777991) is a highly potent and selective CXCR3 antagonist with IC50 of 33 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 2 mg | $258 | In stock | |
| 5 mg | $428 | In stock | |
| 10 mg | $728 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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ACT-777991 (ACT777991) is a highly potent and selective CXCR3 antagonist with IC50 of 33 nM.
ACT-777991 showed dose-dependent efficacy and target engagement in a mouse model of acute lung inflammation.
| M.Wt | 550.48 | |
| Formula | C20H20F6N8O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(R)-1-(2-(2-hydroxyethyl)-4-(2-(trifluoromethyl)-4-(2-(trifluoromethyl)pyrimidin-5-yl)thiazol-5-yl)piperazin-1-yl)-2-(3-methyl-1H-1,2,4-triazol-1-yl)ethan-1-one |
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1. Meyer EA, et al. J Med Chem. 2023 Mar 8. doi: 10.1021/acs.jmedchem.3c00074.
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