ADAM9i | ADAM9 inhibitor | Probechem Biochemicals

Chemical Structure : ADAM9i

CAS No.: 860786-85-2

ADAM9i (ADAM9 specific inhibitor)

Catalog No.: PC-21808Not For Human Use, Lab Use Only.

ADAM9i is a specific small molecule inhibitor of ADAM9 protein with binding KD of 5.9 uM and enzyme IC50 of 5.2 uM, promotes the selective degradation of KRAS and sensitizes pancreatic cancers to chemotherapy.

Packing	Price	Stock
2 mg	$228	In stock
5 mg	$378	In stock
10 mg	$588	In stock
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Biological Activity

ADAM9i is a specific small molecule inhibitor of ADAM9 protein with binding KD of 5.9 uM and enzyme IC50 of 5.2 uM.
ADAM9i promotes the selective degradation of KRAS and sensitizes pancreatic cancers to chemotherapy.

Physicochemical Properties

M.Wt	529.59
Formula	C26H19N5O4S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2,2'-((azanediylbis(thiazole-2,4-diyl))bis(ethane-2,1-diyl))bis(isoindoline-1,3-dione)

References

1. Yu-Kai Huang, et al. Nat Cancer. 2024 Jan 24. doi: 10.1038/s43018-023-00720-x.

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ADAM9i (ADAM9 specific inhibitor)

Biological Activity

Physicochemical Properties

References

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