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Chemical Structure : ADAMTS-5 inhibitor 12
CAS No.: 929634-33-3
Catalog No.: PC-23033Not For Human Use, Lab Use Only.
ADAMTS-5 inhibitor 12 is a potent selective ADAMTS-5 (aggrecanase-2) inhibitor with IC50 of 1.1 uM, >40-fold functional selectivity over ADAMTS-4 (aggrecanase-1).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $138 | In stock | |
| 10 mg | $218 | In stock | |
| 25 mg | $358 | In stock | |
| 50 mg | $558 | In stock | |
| 100 mg | Get quote |
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ADAMTS-5 inhibitor 12 is a potent selective ADAMTS-5 (aggrecanase-2) inhibitor with IC50 of 1.1 uM, >40-fold functional selectivity over ADAMTS-4 (aggrecanase-1).
| M.Wt | 449.91 | |
| Formula | C16H11ClF3N3OS3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
5-((5-((4-Chlorobenzyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one |
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1. Gilbert AM, et al. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1189-92.
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