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ADAMTS-IN-1

Chemical Structure : ADAMTS-IN-1

CAS No.: 2688733-96-0

ADAMTS-IN-1

Catalog No.: PC-23034Not For Human Use, Lab Use Only.

ADAMTS-IN-1 is a potent dual inhibitor of ADAMTS-5 and ADAMTS-4 with IC50s of 8 and 12 nM, respectively, example 37-2 in Patent WO2021158626 A.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ADAMTS-IN-1 is a potent dual inhibitor of ADAMTS-5 and ADAMTS-4 with IC50s of 8 and 12 nM, respectively, example 37-2 in Patent WO2021158626 A.

Physicochemical Properties

M.Wt 424.32
Formula C20H23Cl2N3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(5S)-5-Cyclopropyl-5-[3-[(1R)-7,8-dichloro-1,2,4,5-tetrahydro-1-methyl-3H-3-benzazepin-3-yl]-3-oxopropyl]-2,4-imidazolidinedione

References

1. Patent WO2021158626 A1.

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