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ADAMTS7 inhibitor 3a

Chemical Structure : ADAMTS7 inhibitor 3a

CAS No.:

ADAMTS7 inhibitor 3a (Compound 3a)

Catalog No.: PC-22949Not For Human Use, Lab Use Only.

ADAMTS7 inhibitor 3a is a potent, selective ADAMTS7 inhibitor with Ki of 9 nM, 12-fold selective over ADAMTS5 (Ki=110 nM).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ADAMTS7 inhibitor 3a is a potent, selective ADAMTS7 inhibitor with Ki of 9 nM, 12-fold selective over ADAMTS5 (Ki=110 nM).

Physicochemical Properties

M.Wt 561.58
Formula C27H26F3N3O5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-2-(1-Benzoylpiperidin-4-yl)-N-hydroxy-2-((4'-(trifluoromethyl) [1,1'-biphenyl])-4 sulfonamido)acetamide

References

1. Cuffaro D, et al. RSC Med Chem. 2024 Jun 19;15(8):2806-2825.

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