Catalog No.: PC-60163Not For Human Use, Lab Use Only.
ADX88178 (ADX88178) is a potent, selective, orally active mGluR4 positive allosteric modulator with EC50 of 4 and 9 nM for human and rat mGlu4, respectively.
ADX88178 (ADX88178) is a potent, selective, orally active mGluR4 positive allosteric modulator with EC50 of 4 and 9 nM for human and rat mGlu4, respectively.
ADX88178 displays highly selective for mGluR4 with minimal activities at other mGluRs.
ADX88178 reverses haloperidol-induced catalepsy, improves movement in rodent models of Parkinson's disease.
