Chemical Structure : AEPU
Catalog No.: PC-25595Not For Human Use, Lab Use Only.
AEPU is a moderately water soluble, orally-available, highly potent and selective soluble epoxide hydrolase (sEH) inhibitor with IC50 of 14 nM (human sEH), reduces the development of atherosclerosis in apolipoprotein e-knockout mouse model.
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AEPU is a moderately water soluble, orally-available, highly potent and selective soluble epoxide hydrolase (sEH) inhibitor with IC50 of 14 nM (human sEH), reduces the development of atherosclerosis in apolipoprotein e-knockout mouse model.
M.Wt | 396.57 | |
Formula | C22H40N2O4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Ulu A, et al. J Cardiovasc Pharmacol. 2008 Oct;52(4):314-23.
2. Liu JY, et al. Biochem Pharmacol. 2015 Dec 15;98(4):718-31.
3. Kim IH, et al. J Med Chem. 2007;50:5217–5226.
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