AF-353 (RO-4) | P2X3 antagonist | Probechem Biochemicals

Chemical Structure : AF-353

CAS No.: 865305-30-2

Catalog No.: PC-62754Not For Human Use, Lab Use Only.

AF-353 (RO-4) is a potent, selective and drug-like dual P2X3 and P2X2/3 antagonist with pIC50 of 8.0 and 7.1, respectively.

Packing	Price	Stock
5 mg	$78	In stock
10 mg	$118	In stock
25 mg	$198	In stock
50 mg	$328	In stock
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Biological Activity

AF-353 (RO-4) is a potent, selective and drug-like dual P2X3 and P2X2/3 antagonist with pIC50 of 8.0 and 7.1, respectively.

M.Wt	400.22
Formula	C14H17IN4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine

1. Jung YH, et al. ACS Chem Neurosci. 2017 Jul 19;8(7):1465-1478.