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Chemical Structure : AF-353
CAS No.: 865305-30-2
Catalog No.: PC-62754Not For Human Use, Lab Use Only.
AF-353 (RO-4) is a potent, selective and drug-like dual P2X3 and P2X2/3 antagonist with pIC50 of 8.0 and 7.1, respectively..
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $225 | In stock | |
| 50 mg | $395 | In stock | |
| 100 mg | $685 | In stock | |
| 500 mg | Get quote |
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AF-353 (RO-4) is a potent, selective and drug-like dual P2X3 and P2X2/3 antagonist with pIC50 of 8.0 and 7.1, respectively.
| M.Wt | 400.22 | |
| Formula | C14H17IN4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine |
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1. Jung YH, et al. ACS Chem Neurosci. 2017 Jul 19;8(7):1465-1478.
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