| Cat. No. |
Product Name |
Information |
| PC-27099 |
P2X7R antagonist A20
P2X7 antagonist
|
P2X7R antagonist A20 (Compound 9q) is a potent, selective antagonist of ATP-gated channel P2X7 receptor (P2X7R) with IC50 of 18 nM (hP2X7), exhibits non-competitive negative allosteric mode of antagonism. |
| PC-26569 |
UB-ALT-P2
P2X7 antagonist
|
UB-ALT-P2 is a potent and selective brain-penetrant negative allosteric modulator / antagonist of ATP-gated P2X7 receptor (P2X7R) with IC50 of 1.3 nM. |
| PC-25132 |
PPADS tetrasodium
P2X receptor antagonist
|
PPADS tetrasodiuma is a non-selective P2X receptor antagonist, inhibits recombinant P2X1, P2X12, P2X13, P2X15 with IC50 of 1-2.6 uM. |
| PC-22910 |
AZ11645373
P2X7 antagonist
|
AZ11645373 is a selective and potent antagonist of human P2X7 receptor, inhibits ATP-mediated release of IL-1β in LPS-stimulated THP-1 monocytes with Kb of 92 nM. |
| PC-21244 |
BX430
P2X4 antagonist
|
BX430 is a potent, highly selective and allosteric antagonist of P2X4 receptor channel with IC50 of 0.54 uM. |
| PC-20741 |
BLU-5937
P2X3 antagonist
|
BLU-5937 (Camlipixant, BLU5937) is a potent, selective and non-competitive P2X3 homotrimeric receptor antagonist with IC50 of 25 and 92 nM for human and rat P2X3 receptors, repsectively. |
| PC-20738 |
Filapixant
P2X3 antagonist
|
Filapixant (BAY1902607) is a potent, selective P2X3 receptor antagonist, shows a substantially higher in vitro selectivity for P2X3 over P2X2 when compared with Eliapixant (BAY1817080, Cat# PC-72754). |
| PC-49765 |
NF449
P2X1 antagonist
|
NF449 (NF-449) is a highly potent, selective and reversible competitive human P2X1 receptor antagonist with IC50 of 0.05 nM. |
| PC-73112 |
BAY-1797
P2X4 antagonist
|
BAY-1797 (BAY1797) is a potent and selective P2X4 inhibitor/antagonist with IC50 of 211 nM (hP2X4). |
| PC-72754 |
Eliapixant
P2X3 antagonist
|
Eliapixant (BAY 1817080) is a potent, selective P2X3 receptor antagonist with IC50 of 8 nM (hP2X3). |
| PC-72721 |
5-BDBD
P2X4 antagonist
|
5-BDBD is a potent and selective P2X4 receptor (P2X4R) antagonist, inhibits P2X4-mediated currents in CHO cells with IC50 of 0.5 uM. |
| PC-72666 |
Sivopixant
P2X3 antagonist
|
Sivopixant (S-600918) is a potent and selective P2X3 homotrimers antagonist with IC50 of 4.2 nM, 250-fold selectivity over P2X2/3 heterotrimer (IC50=1,100 nM). |
