| Cat. No. |
Product Name |
Information |
| PC-22645 |
GSK1482160
P2X7 NAM
|
GSK1482160 is an orally available allosteric P2X7 receptor negative allosteric modulator (NAM). |
| PC-22526 |
NP-1815-PX sodium
P2X4 antagonist
|
NP-1815-PX sodium is a potent, selective P2X4 receptor (P2X4R) antagonist, inhibits P2X4R-mediated [Ca2+]i increase in hP2X4R-1321N1 cells with IC50 of 0.26 μM. |
| PC-22525 |
NP-1815-PX
P2X4 antagonist
|
NP-1815-PX is a potent, selective P2X4 receptor (P2X4R) antagonist, inhibits P2X4R-mediated [Ca2+]i increase in hP2X4R-1321N1 cells with IC50 of 0.26 μM. |
| PC-21904 |
A438079 hydrochloride
P2X7 inhibitor
|
A438079 hydrochloride is a selective, competitive P2X7 receptor antagonist with pIC50 of 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell line. |
| PC-21903 |
A438079
P2X7 inhibitor
|
A438079 is a selective, competitive P2X7 receptor antagonist with pIC50 of 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell line. |
| PC-21244 |
BX430
P2X4 antagonist
|
BX430 is a potent, highly selective and allosteric antagonist of P2X4 receptor channel with IC50 of 0.54 uM. |
| PC-20742 |
DT-0111
P2X2/3 antagonist
|
DT-0111 (DT0111) is a selective and effective, water-soluble antagonist at P2X2/3R, does not activate or block P2YR, inhibits ATP-induced current in nodose ganglionic cells with IC50 of 0.3 uM. |
| PC-20738 |
Filapixant
P2X3 antagonist
|
Filapixant (BAY1902607) is a potent, selective P2X3 receptor antagonist, shows a substantially higher in vitro selectivity for P2X3 over P2X2 when compared with Eliapixant (BAY1817080, Cat# PC-72754). |
| PC-49765 |
NF449
P2X1 inhibitor
|
NF449 (NF-449) is a highly potent, selective and reversible competitive human P2X1 receptor antagonist with IC50 of 0.05 nM. |
| PC-73112 |
BAY-1797
P2X4 antagonist
|
BAY-1797 (BAY1797) is a potent and selective P2X4 inhibitor/antagonist with IC50 of 211 nM (hP2X4). |
| PC-63496 |
AZ-2
|
AZ-2 is a small molecule inducer of ABCA1 and apoE that act through indirect activation of the LXR pathway, shows purinergic receptor P2X7 antagonist activity. |
| PC-63495 |
AZ-1
|
AZ-1 is a small molecule inducer of ABCA1 and apoE that act through indirect activation of the LXR pathway, shows purinergic receptor P2X7 antagonist activity. |
