RO-51 |P2X(3)/P2X(2/3) antagonist Probechem Biochemicals

Chemical Structure : RO-51

Catalog No.: PC-62755Not For Human Use, Lab Use Only.

RO-51 is a potent, selective and drug-like dual P2X3 and P2X2/3 antagonist with pIC50 of 8.7 and 8.3, respectively.

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Biological Activity

RO-51 is a potent, selective and drug-like dual P2X3 and P2X2/3 antagonist with pIC50 of 8.7 and 8.3, respectively.

M.Wt	474.299
Formula	C17H23IN4O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((4-amino-5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidin-2-yl)amino)propane-1,3-diol

1. Jahangir A, et al. Bioorg Med Chem Lett. 2009 Mar 15;19(6):1632-5.

2. Serrano A, et al. J Neurosci. 2012 Aug 22;32(34):11890-6.