Chemical Structure : AF38469
CAS No.: 1531634-31-7
Catalog No.: PC-43219Not For Human Use, Lab Use Only.
AF38469 is a potent, selective, orally bioavailable Sortilin inhibitor with IC50 of 330 nM.
Packing | Price | Stock | Quantity |
---|---|---|---|
10 mg | $198 | In stock | |
25 mg | $328 | In stock | |
100 mg | $798 | In stock | |
200 mg | Get quote | ||
1 g | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
AF38469 is a potent, selective, orally bioavailable Sortilin inhibitor with IC50 of 330 nM.
AF38469 shows no activity against the NTR1 receptor as well as a panel of targets known to bind acidic molecules (δ-Opioid, GPR40, PPARδ, EP1, Angiotensin AT1, Endothelin ETA/B, MMP-12).
M.Wt | 324.2546 | |
Formula | C15H11F3N2O3 | |
Appearance | Solid | |
Storage |
|
|
Solubility |
DMSO: ≥ 43 mg/mL |
|
Chemical Name/SMILES |
Benzoic acid, 2-[[(6-methyl-2-pyridinyl)amino]carbonyl]-5-(trifluoromethyl)- |
1. Schrøder TJ, et al. Bioorg Med Chem Lett. 2014 Jan 1;24(1):177-80.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright