AF38469 |CAS:1531634-31-7 Probechem Biochemicals

Chemical Structure : AF38469

CAS No.: 1531634-31-7

AF38469 (AF-38469)

Catalog No.: PC-43219Not For Human Use, Lab Use Only.

AF38469 is a potent, selective, orally bioavailable Sortilin inhibitor with IC50 of 330 nM.

Packing	Price	Stock
10 mg	$198	In stock
25 mg	$328	In stock
100 mg	$798	In stock
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Biological Activity

AF38469 is a potent, selective, orally bioavailable Sortilin inhibitor with IC50 of 330 nM.
AF38469 shows no activity against the NTR1 receptor as well as a panel of targets known to bind acidic molecules (δ-Opioid, GPR40, PPARδ, EP1, Angiotensin AT1, Endothelin ETA/B, MMP-12).

Physicochemical Properties

M.Wt	324.2546
Formula	C15H11F3N2O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: ≥ 43 mg/mL
Chemical Name/SMILES	Benzoic acid, 2-[[(6-methyl-2-pyridinyl)amino]carbonyl]-5-(trifluoromethyl)-

References

1. Schrøder TJ, et al. Bioorg Med Chem Lett. 2014 Jan 1;24(1):177-80.

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AF38469 (AF-38469)

Biological Activity

Physicochemical Properties

References

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