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Chemical Structure : AF40431
CAS No.: 181125-92-8
Catalog No.: PC-35821Not For Human Use, Lab Use Only.
AF40431 (AF-40431) is the first reported small-molecule ligand of the VPS10P family sorting receptor Sortilin with IC50 of 4.4 uM, binds in the neurotensin-binding site of sortilin..
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $238 | In stock | |
| 10 mg | $378 | In stock | |
| 25 mg | $578 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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AF40431 (AF-40431) is the first reported small-molecule ligand of the VPS10P family sorting receptor Sortilin with IC50 of 4.4 uM, binds in the neurotensin-binding site of sortilin.
| M.Wt | 319.357 | |
| Formula | C17H21NO5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
((7-hydroxy-4-methyl-2-oxo-2H-chromen-8-yl)methyl)-L-leucine |
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1. Andersen JL, et al. Acta Crystallogr D Biol Crystallogr. 2014 Feb;70(Pt 2):451-60.
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