AF40431 |CAS:181125-92-8 Probechem Biochemicals

Chemical Structure : AF40431

CAS No.: 181125-92-8

AF40431 (AF 40431;AF 40431)

Catalog No.: PC-35821Not For Human Use, Lab Use Only.

AF40431 (AF-40431) is the first reported small-molecule ligand of the VPS10P family sorting receptor Sortilin with IC50 of 4.4 uM, binds in the neurotensin-binding site of sortilin..

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10 mg	$378	In stock
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Biological Activity

AF40431 (AF-40431) is the first reported small-molecule ligand of the VPS10P family sorting receptor Sortilin with IC50 of 4.4 uM, binds in the neurotensin-binding site of sortilin.

Physicochemical Properties

M.Wt	319.357
Formula	C17H21NO5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	((7-hydroxy-4-methyl-2-oxo-2H-chromen-8-yl)methyl)-L-leucine

References

1. Andersen JL, et al. Acta Crystallogr D Biol Crystallogr. 2014 Feb;70(Pt 2):451-60.

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AF40431 (AF 40431;AF 40431)

Biological Activity

Physicochemical Properties

References

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