Chemical Structure : AGK2
CAS No.:
304896-28-4
AGK2
(SIRT2 inhibitor AGK2)
Catalog No. : PC-38543Not For Human Use, Lab Use Only.
AGK2 is a cell-permeable, selective inhibitor of SIRT2 with IC50 of 3.2 uM, shows minimally affects either SIRT1 or SIRT3 at 10-fold higher levels.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-3854301
Biological Activity
AGK2 is a cell-permeable, selective inhibitor of SIRT2 with IC50 of 3.2 uM, shows minimally affects either SIRT1 or SIRT3 at 10-fold higher levels.
Physicochemical Properties
M.Wt
434.3
Formula
C23H13Cl2N3O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
2-cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-5-quinolinyl-2-propenamide
References
1. Outeiro TF, et al. Science
2. Kumar V, et al. Eur J Biochem.
3. Giammona LM, et al. Exp Hematol.
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