Chemical Structure : AGN196996
CAS No.: 958295-17-5
Catalog No.: PC-21162Not For Human Use, Lab Use Only.
AGN 196996 (IRX6696) is a potent selective RARα antagonist with Ki of 2 nM, shows little to no activity against RARβ and RARγ.
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AGN196996 (IRX6696) is a potent selective RARα antagonist with Ki of 2 nM, shows little to no activity against RARβ and RARγ.
AGN196996 (IRX6696) blocks the gene transcriptional activity induced by ATRA and other RAR agonists.
M.Wt | 482.33 | |
Formula | C24H20BrNO5 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
4-[[3-Bromo-4-ethoxy-5-(4-methylbenzoyl)benzoyl]amino]benzoic acid |
1. Hammond LA, et al. Br J Cancer. 2001 Aug 3;85(3):453-62.
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