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AGN196996

Chemical Structure : AGN196996

CAS No.: 958295-17-5

AGN196996 (AGN 196996, IRX-6696, IRX6696)

Catalog No.: PC-21162Not For Human Use, Lab Use Only.

AGN 196996 (IRX6696) is a potent selective RARα antagonist with Ki of 2 nM, shows little to no activity against RARβ and RARγ.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

AGN196996 (IRX6696) is a potent selective RARα antagonist with Ki of 2 nM, shows little to no activity against RARβ and RARγ.
AGN196996 (IRX6696) blocks the gene transcriptional activity induced by ATRA and other RAR agonists.

Physicochemical Properties

M.Wt 482.33
Formula C24H20BrNO5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-[[3-Bromo-4-ethoxy-5-(4-methylbenzoyl)benzoyl]amino]benzoic acid

References

1. Hammond LA, et al. Br J Cancer. 2001 Aug 3;85(3):453-62.

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