AGN196996 | RARα antagonist | Probechem Biochemicals

Chemical Structure : AGN196996

CAS No.: 958295-17-5

AGN196996 (AGN 196996, IRX-6696, IRX6696)

Catalog No.: PC-21162Not For Human Use, Lab Use Only.

AGN 196996 (IRX6696) is a potent selective RARα antagonist with Ki of 2 nM, shows little to no activity against RARβ and RARγ.

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5 mg	$288	In stock
10 mg	$428	In stock
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Biological Activity

AGN196996 (IRX6696) is a potent selective RARα antagonist with Ki of 2 nM, shows little to no activity against RARβ and RARγ.
AGN196996 (IRX6696) blocks the gene transcriptional activity induced by ATRA and other RAR agonists.

Physicochemical Properties

M.Wt	482.33
Formula	C24H20BrNO5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-[[3-Bromo-4-ethoxy-5-(4-methylbenzoyl)benzoyl]amino]benzoic acid

References

1. Hammond LA, et al. Br J Cancer. 2001 Aug 3;85(3):453-62.

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AGN196996 (AGN 196996, IRX-6696, IRX6696)

Biological Activity

Physicochemical Properties

References

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