AK778 (Col001) | HSP47-collagen inhibitor

Chemical Structure : AK778

AK778 (AK 778, Col001)

Catalog No.: PC-62621Not For Human Use, Lab Use Only.

AK778 (Col001) is a small-molecule compound that inhibits the interaction of Hsp47 with collagen, competitively inhibits the interaction and causes the inhibition of collagen secretion by destabilizing the collagen triple helix.

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Biological Activity

AK778 (Col001) is a small-molecule compound that inhibits the interaction of Hsp47 with collagen, competitively inhibits the interaction and causes the inhibition of collagen secretion by destabilizing the collagen triple helix.

Physicochemical Properties

M.Wt	462.509
Formula	C28H22N4O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(((5-(1H-benzo[d]imidazol-2-yl)-2-methylphenyl)imino)methyl)-4-benzyl-6-nitrophenol

References

1. Ito S, et al. J Biol Chem. 2017 Dec 8;292(49):20076-20085.

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AK778 (AK 778, Col001)

Biological Activity

Physicochemical Properties

References

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