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AKB-6899

Chemical Structure : AKB-6899

CAS No.: 1007377-55-0

AKB-6899 (AKB6899)

Catalog No.: PC-26202Not For Human Use, Lab Use Only.

AKB-6899 is a small molecule prolyl hydroxylase domain 3 (PHD3) inhibitor and selective HIF-2α stabilizer, enhances monocyte and macrophage production of sVEGFR-1.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

AKB-6899 is a small molecule prolyl hydroxylase domain 3 (PHD3) inhibitor and selective HIF-2α stabilizer, enhances monocyte and macrophage production of sVEGFR-1.

Physicochemical Properties

M.Wt 290.25
Formula C14H11FN2O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(5-(3-Fluorophenyl)-3-hydroxypicolinoyl)glycine

References

1. Roda JM, et al. J Immunol. 2012 Sep 15;189(6):3168-77.

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