Chemical Structure : AKB-9778
CAS No.: 1008510-37-9
Catalog No.: PC-61676Not For Human Use, Lab Use Only.
AKB-9778 (Razuprotafib) is a potent, selective inhibitor of vascular endothelial protein tyrosine phosphatase (VE-PTP, HPTPβ) with IC50 of 17 pM.
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M.Wt | 586.70 | |
Formula | C26H26N4O6S3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(4-((S)-2-((S)-2-((methoxycarbonyl)amino)-3-phenylpropanamido)-2-(2-(thiophen-2-yl)thiazol-4-yl)ethyl)phenyl)sulfamic acid |
1. Goel S, et al. J Natl Cancer Inst. 2013 Aug 21;105(16):1188-201.
2. Shen J, et al. J Clin Invest. 2014 Oct;124(10):4564-76.
3. Amarasinghe KK, et al. Bioorg Med Chem Lett. 2006 Aug 15;16(16):4252-6.
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