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Chemical Structure : ALKBH1 inhibitor 13h
Catalog No.: PC-21915Not For Human Use, Lab Use Only.
ALKBH1 inhibit 13h is a potent, isoform selective, and cell-active DNA 6mA demethylase ALKBH1 inhibitor with 26 nM and 1.39 uM in FP and enzyme activity assay, respectively.
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ALKBH1 inhibit 13h is a potent, isoform selective, and cell-active DNA 6mA demethylase ALKBH1 inhibitor with 26 nM and 1.39 uM in FP and enzyme activity assay, respectively.
ALKBH1 inhibit 13h shows high binding affinity with ITC KD value of 112 nM.
ALKBH1 inhibit 13h engages ALKBH1 and modulates the 6mA levels in cells.
| M.Wt | 380.28 | |
| Formula | C16H11F3N4O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Liang Xiong, et al. J Am Chem Soc. 2024 Mar 4. doi: 10.1021/jacs.4c00194.
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