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ALKBH5 inhibitor Ena15

Chemical Structure : ALKBH5 inhibitor Ena15

CAS No.: 956935-02-7

ALKBH5 inhibitor Ena15

Catalog No.: PC-23676Not For Human Use, Lab Use Only.

Ena15 is a selective small molecule m6A demethylation enzyme ALKBH5 inhibitor with IC50 of 18.3 uM, also enhances the demethylase activity of FTO.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Ena15 is a selective small molecule m6A demethylation enzyme ALKBH5 inhibitor with IC50 of 18.3 uM, also enhances the demethylase activity of FTO.

Physicochemical Properties

M.Wt 438.58
Formula C28H30N4O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-benzyl-N-(4-ethylbenzyl)-3,5-dimethyl-N-(pyridin-3-ylmethyl)-1H-pyrazole-4-carboxamide

References

1. Takahashi H, et al. Chem Biol Drug Des. 2022 Jul;100(1):1-12.

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