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AM-2201

Chemical Structure : AM-2201

CAS No.: 335161-24-5

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AM-2201 (AM 2201;AM2201)

Catalog No.: PC-60761Not For Human Use, Lab Use Only.

AM-2201 is a synthetic cannabinoid that acts as a potent, nonselective full agonist for the cannabinoid receptor with EC50 of 38 and 58 nM for CB1 and CB2, respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

AM-2201 is a synthetic cannabinoid that acts as a potent, nonselective full agonist for the cannabinoid receptor with EC50 of 38 and 58 nM for CB1 and CB2, respectively.
AM-2201 dose-dependently induces hypothermia and reduces heart rate at doses of 0.3-10 mg/kg in mice.

Physicochemical Properties

M.Wt 359.4
Formula C24H22FNO
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

[1-(5-fluoropentyl)-1H-indol-3-yl](naphthalene-1-yl)methanone

References

1. McQuade D, et al. Eur J Clin Pharmacol. 2013 Mar;69(3):373-6.

2. Sobolevsky T, et al. Drug Test Anal. 2012 Oct;4(10):745-53.

3. Banister SD, et al. ACS Chem Neurosci. 2015 Aug 19;6(8):1445-58.

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