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Chemical Structure : AM-5308
CAS No.: 2410796-89-1
Catalog No.: PC-49614Not For Human Use, Lab Use Only.
AM-5308 is a potent, selective mitotic kinesin KIF18A inhibitor with IC50 of 47 nM in kinesin-8 microtubule (MT)-ATPase motor assays.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $388 | In stock | |
| 10 mg | $558 | In stock | |
| 25 mg | Get quote | ||
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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AM-5308 is a potent, selective mitotic kinesin KIF18A inhibitor with IC50 of 47 nM in kinesin-8 microtubule (MT)-ATPase motor assays.
AM-5308 exhibited good specificity against a panel of diverse kinesin motor proteins, except for the KIF19A motor (IC50=224 nM).
| M.Wt | 529.66 | |
| Formula | C26H35N5O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(R)-4-((2-hydroxyethyl)sulfonamido)-N-(6-(2-methylmorpholino)pyridin-2-yl)-2-(6-azaspiro[2.5]octan-6-yl)benzamide |
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