AM10257 | CB2 antagonist | Probechem Biochemicals

Chemical Structure : AM10257

Catalog No.: PC-22167Not For Human Use, Lab Use Only.

AM10257 is a potent, selective cannabinoid receptor 2 (CB2) antagonist with IC50 of 47 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

AM10257 is a potent, selective cannabinoid receptor 2 (CB2) antagonist with IC50 of 47 nM.

M.Wt	421.59
Formula	C26H35N3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(adamantan-1-yl)-1-(5-hydroxypentyl)-4-methyl-5-phenyl-1H-pyrazole-3-carboxamide

1. Hu T, et al. J Med Chem. 2021 Sep 23;64(18):13752-13765.

2. Li X, et al. Cell. 2019 Jan 24;176(3):459-467.e13.