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AMY-101

Chemical Structure : AMY-101

CAS No.: 1427001-89-5

AMY-101 (Cp40, AMY101)

Catalog No.: PC-72455Not For Human Use, Lab Use Only.

AMY-101 (Cp40) is a peptidic inhibitor of the central complement component C3 for the management of patients with ARDS caused by SARS-CoV-2 infection.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

AMY-101 (Cp40) is a peptidic inhibitor of the central complement component C3 for the management of patients with ARDS caused by SARS-CoV-2 infection.
AMY-101 is a novel complement C3-targeted therapeutic based on the 3 rd-generation compstatin analog Cp40.

Physicochemical Properties

M.Wt 1789.11
Formula C83H117N23O18S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

YICV-{Trp(Me)}-QDW-{Sar}-AHRC-{N(Me)Ile}-NH2 (Disulfide bridge:Cys3-Cys13)

References

1. Bostanci N, et al. J Proteome Res. 2018 Sep 7;17(9):3153-3175.

2. Reis ES, et al. Clin Immunol. 2018 Dec;197:96-106.

3. Mastellos DC, et al. Clin Immunol. 2020 Nov;220:108598.

4. Hasturk H, et al. J Clin Invest. 2021 Dec 1;131(23):e152973.

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