Chemical Structure : AMY-101
CAS No.: 1427001-89-5
Catalog No.: PC-72455Not For Human Use, Lab Use Only.
AMY-101 (Cp40) is a peptidic inhibitor of the central complement component C3 for the management of patients with ARDS caused by SARS-CoV-2 infection.
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AMY-101 (Cp40) is a peptidic inhibitor of the central complement component C3 for the management of patients with ARDS caused by SARS-CoV-2 infection.
AMY-101 is a novel complement C3-targeted therapeutic based on the 3 rd-generation compstatin analog Cp40.
M.Wt | 1789.11 | |
Formula | C83H117N23O18S2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
YICV-{Trp(Me)}-QDW-{Sar}-AHRC-{N(Me)Ile}-NH2 (Disulfide bridge:Cys3-Cys13) |
1. Bostanci N, et al. J Proteome Res. 2018 Sep 7;17(9):3153-3175.
2. Reis ES, et al. Clin Immunol. 2018 Dec;197:96-106.
3. Mastellos DC, et al. Clin Immunol. 2020 Nov;220:108598.
4. Hasturk H, et al. J Clin Invest. 2021 Dec 1;131(23):e152973.
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