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AN7973

Chemical Structure : AN7973

CAS No.: 1620899-32-2

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AN7973 (AN-7973)

Catalog No.: PC-72991Not For Human Use, Lab Use Only.

AN7973 (AN-7973) is a novel drug candidate for treatment of cryptosporidiosis, potently inhibits multiple C. parvum isolates and the C. hominis TU502 isolate in vitro.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    AN7973 (AN-7973) is a novel drug candidate for treatment of cryptosporidiosis, potently inhibits multiple C. parvum isolates and the C. hominis TU502 isolate in vitro.
    AN7973 inhibits intracellular Cryptosporidium replication (EC50=0.13 uM), selectively inhibits Cryptosporidium development.

    Physicochemical Properties

    M.Wt 381.62
    Formula C19H17BClN3O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-chloro-N-(1-hydroxy-3,3-dimethyl-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)-4-(1H-pyrazol-1-yl)benzamide

    References

    1. Begolo D, et al. PLoS Pathog. 2018 Sep 25;14(9):e1007315.

    2. Lunde CS, et al. Nat Commun. 2019 Jun 27;10(1):2816.

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