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ANAVEX2-73

Chemical Structure : ANAVEX2-73

CAS No.: 195615-84-0

ANAVEX2-73 (Blarcamesine hydrochloride, ANAVEX 2-73)

Catalog No.: PC-38233Not For Human Use, Lab Use Only.

ANAVEX2-73 (Blarcamesine) hydrochloride is a potent Sigma-1 receptor agonist with IC50 of 860 nM, and muscarinic receptor modulator with neuroprotective effects.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

ANAVEX2-73 (Blarcamesine) hydrochloride is a potent Sigma-1 receptor agonist with IC50 of 860 nM, and muscarinic receptor modulator with neuroprotective effects.

Physicochemical Properties

M.Wt 317.857
Formula C19H24ClNO
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Tetrahydro-N, N-dimethyl-2, 2-diphenyl-3-furanmethanamine hydrochloride

References

1. Lahmy V, et al. Neuropsychopharmacology. 2013 Aug;38(9):1706-23. 

2. Lahmy V, et al. Front Cell Neurosci. 2015 Jan 20;8:463.

3. Kaufmann WE, et al. Pharmacol Biochem Behav. 2019 Dec;187:172796.

4. Ye N, et al. J Med Chem. 2020 Dec 24;63(24):15187-15217.

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