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AP1867-2-(carboxymethoxy)

Chemical Structure : AP1867-2-(carboxymethoxy)

CAS No.: 2230613-03-1

AP1867-2-(carboxymethoxy) (FKBP12 Ligand)

Catalog No.: PC-35860Not For Human Use, Lab Use Only.

AP1867-2-(carboxymethoxy) is a ligand of FKBP12, binds to CRBN ligand via a linker to form dTAG molecules.

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Biological Activity

AP1867-2-(carboxymethoxy) is a ligand of FKBP12, binds to CRBN ligand via a linker to form dTAG molecules.

Physicochemical Properties

M.Wt 693.79
Formula C38H47NO11
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(2-((R)-3-(3,4-dimethoxyphenyl)-1-(((S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carbonyl)oxy)propyl)phenoxy)acetic acid

References

1. Nabet B, et al. Nat Chem Biol. 2018 May;14(5):431-441.

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