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Chemical Structure : APA modulator T5
Catalog No.: PC-35767Not For Human Use, Lab Use Only.
APA modulator T5 is a small modulator of alternative polyadenylation (APA), modulates endogenous APA via nonkinase-mediated pathways and promotes distal-to-proximal (DtoP) APA usage in multiple transcripts.
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APA modulator T5 is a small modulator of alternative polyadenylation (APA), modulates endogenous APA via nonkinase-mediated pathways and promotes distal-to-proximal (DtoP) APA usage in multiple transcripts.
APA modulator T5 predominantly induced CR-APA and UTR-APA.
APA modulator T5 exhibits high potency and selectivity for APA modulation, inducing a preference for the use of proximal intronic poly(A) CSs with long intron regions through the PABPN1 pathway.
APA modulator T5 is a valuable tool for increasing the understanding of the molecular mechanisms of APA and splicing.
| M.Wt | 329.403 | |
| Formula | C21H19N3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Araki S, et al. Cell Chem Biol. 2018 Sep 26. pii: S2451-9456(18)30301-5.
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