Catalog No.: PC-50004Not For Human Use, Lab Use Only.
AQX-1125 (Rosiptor) is a specific, orally bioavailable SHIP1 activator with no effect on functional androgen, oestrogen, oestrogen-related receptor α, glucocorticoid, mineralocorticoid and progesterone receptor at 30 uM.
AQX-1125 (Rosiptor) is a specific, orally bioavailable SHIP1 activator with no effect on functional androgen, oestrogen, oestrogen-related receptor α, glucocorticoid, mineralocorticoid and progesterone receptor at 30 uM.
AQX-1125 (Rosiptor) inhibits the pAkt (S473) in MOLT-4 cells, and inhibits cytokine release in mixed splenocytes.
AQX-1125 (Rosiptor) significantly decreases β-hexosaminidase release in mouse BMMCs.
AQX-1125 (Rosiptor) inhibits chemotaxis in human mononuclear cells (EC50=0.26 uM).
AQX-1125 (Rosiptor) suppresses leukocyte accumulation and inflammatory mediator release in rodent models of pulmonary inflammation and allergy.
Physicochemical Properties
M.Wt
321.505
Formula
C20H35NO2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Room temperature in continental US; may vary elsewhere
