Catalog No.: PC-50005Not For Human Use, Lab Use Only.
AQX 1125 acetate (Rosiptor) is a sepecific, orally bioavailable SHIP1 activator with no effect on functional androgen, oestrogen, oestrogen-related receptor α, glucocorticoid, mineralocorticoid and progesterone receptor at 30 uM.
AQX 1125 acetate (Rosiptor) is a sepecific, orally bioavailable SHIP1 activator with no effect on functional androgen, oestrogen, oestrogen-related receptor α, glucocorticoid, mineralocorticoid and progesterone receptor at 30 uM.
AQX 1125 acetate (Rosiptor) inhibits the pAkt (S473) in MOLT-4 cells, and inhibits cytokine release in mixed splenocytes.
AQX 1125 acetate (Rosiptor) significantly decreases β-hexosaminidase release in mouse BMMCs.
AQX 1125 acetate (Rosiptor) inhibits chemotaxis in human mononuclear cells (EC50=0.26 uM).
AQX 1125 acetate (Rosiptor) suppresses leukocyte accumulation and inflammatory mediator release in rodent models of pulmonary inflammation and allergy.
Physicochemical Properties
M.Wt
381.557
Formula
C22H39NO4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Room temperature in continental US; may vary elsewhere
