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AR102

Chemical Structure : AR102

CAS No.: 3021566-15-1

AR102 (AR-102)

Catalog No.: PC-23225Not For Human Use, Lab Use Only.

AR102 is a potent, selective, and broad-spectrum activity against schistosome species.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

AR102 is a potent, selective, and broad-spectrum activity against schistosome species.
AR102 is a potent antischistosomal with ED50 values of 7.8 and 18 mg/kg against the adult and juvenile stages of S. mansoni in infected mice and ED50 values of 8.5 and 6.3 mg/kg against adult S. haematobium in infected hamsters and adult S. japonicum in infected mice, respectively.

Physicochemical Properties

M.Wt 292.29
Formula C13H7D6F3N2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(3-(1,1-difluoroethyl)-4-fluorophenyl)-5,5-bis(methyl-d3)imidazolidine-2,4-dione

References

1. Leas DA, et al. ACS Infect Dis. 2024 Oct 18. doi: 10.1021/acsinfecdis.4c00677.

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