ARM-1 |CAS:68729-05-5 Probechem Biochemicals

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Chemical Structure : ARM-1

CAS No.: 68729-05-5

ARM-1 (ARM1, 4BSA)

Catalog No.: PC-70333Not For Human Use, Lab Use Only.

ARM-1 is a novel LTA4 hydrolase (LTA4H) inhibitor that inhibits LTB4 synthesis in human neutrophils with IC50 of 0.5 uM.

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10 mg	$138	In stock
25 mg	$218	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

ARM-1 is a novel LTA4 hydrolase (LTA4H) inhibitor that inhibits LTB4 synthesis in human neutrophils with IC50 of 0.5 uM.
ARM-1 selectively blocks conversion of LTA4 into LTB4, sparing the enzyme's anti-inflammatory aminopeptidase activity.
ARM-1 represents a new class of LTA4 hydrolase inhibitor that holds promise for improved anti-inflammatory properties.

Physicochemical Properties

M.Wt	268.4
Formula	C16H16N2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(4-benzylphenyl)thiazol-2-amine

References

1. Stsiapanava A, et al. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4227-32.

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ARM-1 (ARM1, 4BSA)

Biological Activity

Physicochemical Properties

References

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