Chemical Structure : ARM-1
CAS No.: 68729-05-5
Catalog No.: PC-70333Not For Human Use, Lab Use Only.
ARM-1 is a novel LTA4 hydrolase (LTA4H) inhibitor that inhibits LTB4 synthesis in human neutrophils with IC50 of 0.5 uM.
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ARM-1 is a novel LTA4 hydrolase (LTA4H) inhibitor that inhibits LTB4 synthesis in human neutrophils with IC50 of 0.5 uM.
ARM-1 selectively blocks conversion of LTA4 into LTB4, sparing the enzyme's anti-inflammatory aminopeptidase activity.
ARM-1 represents a new class of LTA4 hydrolase inhibitor that holds promise for improved anti-inflammatory properties.
M.Wt | 268.4 | |
Formula | C16H16N2S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
4-(4-benzylphenyl)thiazol-2-amine |
1. Stsiapanava A, et al. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4227-32.
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