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Chemical Structure : ARN23765
Catalog No.: PC-38208Not For Human Use, Lab Use Only.
ARN23765 (ARN 23765) is a highly potent, pharmacological corrector of the mutant CFTR chloride channel with EC50 of 38 pM in cellular assays.
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ARN23765 (ARN 23765) is a highly potent, pharmacological corrector of the mutant CFTR chloride channel with EC50 of 38 pM in cellular assays.
ARN23765 is more than 5000-fold lower compared to presently available corrector drugs.
ARN23765 also showed high efficacy, synergy with other types of correctors, and compatibility with chronic VX-770 potentiator.
| M.Wt | 615.513 | |
| Formula | C30H22F5N3O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Nicoletta Pedemonte, et al. Sci Adv. 2020 Feb 21;6(8):eaay9669.
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