ARP101 (ARP-101) is a selective MMP-2 inhibitor, induces autophagy-associated cell death in cancer cells.
ARP101 (ARP-101) was highly effective in inducing the formation of autophagosome and conversion of LC3I into LC3II.
ARP101-induced autophagy was completely blocked in mouse embryo fibroblasts that lacked autophagy related gene 5 (ATG5(-/-) MEF).
ARP101 inhibits α-MSH-stimulated melanogenesis by regulation of autophagy in melanocytes.
