Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : ARP101
CAS No.: 849773-63-3
Catalog No.: PC-35730Not For Human Use, Lab Use Only.
ARP101 (ARP-101) is a selective MMP-2 inhibitor, induces autophagy-associated cell death in cancer cells.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $238 | In stock | |
| 10 mg | $388 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
ARP101 (ARP-101) is a selective MMP-2 inhibitor, induces autophagy-associated cell death in cancer cells.
ARP101 (ARP-101) was highly effective in inducing the formation of autophagosome and conversion of LC3I into LC3II.
ARP101-induced autophagy was completely blocked in mouse embryo fibroblasts that lacked autophagy related gene 5 (ATG5(-/-) MEF).
ARP101 inhibits α-MSH-stimulated melanogenesis by regulation of autophagy in melanocytes.
| M.Wt | 406.497 | |
| Formula | C20H26N2O5S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(R)-N-hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-sulfonamido)-3-methylbutanamide |
|
1. Jo YK, et al. Biochem Biophys Res Commun. 2011 Jan 28;404(4):1039-43.
2. Kim ES, et al. FEBS Lett. 2013 Dec 11;587(24):3955-60.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
