ARS-1323 |CAS:1698024-73-5 Probechem Biochemicals

Chemical Structure : ARS-1323

CAS No.: 1698024-73-5

ARS-1323 (ARS1323)

Catalog No.: PC-62496Not For Human Use, Lab Use Only.

ARS1323 is a racemic mixture of ARS-1620/R-atropisomer, ARS-1620 is a potent, specific and covalent KRAS G12C inhibitor with >10-fold improved potency over the initial ARS-853..

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10 mg	$288	In stock
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Biological Activity

ARS1323 is a racemic mixture of ARS-1620/R-atropisomer, ARS-1620 is a potent, specific and covalent KRAS G12C inhibitor with >10-fold improved potency over the initial ARS-853.

Physicochemical Properties

M.Wt	430.84
Formula	C21H17ClF2N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one

References

1. Janes MR, et al. Cell. 2018 Jan 25;172(3):578-589.e17.

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ARS-1323 (ARS1323)

Biological Activity

Physicochemical Properties

References

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