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ARS-1630

Chemical Structure : ARS-1630

CAS No.: 1698055-86-5

ARS-1630 (ARS1630;ARS1620 R-atropisomer)

Catalog No.: PC-62495Not For Human Use, Lab Use Only.

ARS-1630 is the R-conformational atropisomer of ARS-1620, 1,000-fold less potent than ARS-1620 (1.2 ± 0.6 M-1s-1) and thus acts as a unique inactive control compound..

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Biological Activity

ARS-1630 is the R-conformational atropisomer of ARS-1620, 1,000-fold less potent than ARS-1620 (1.2 ± 0.6 M-1s-1) and thus acts as a unique inactive control compound.

Physicochemical Properties

M.Wt 430.84
Formula C21H17ClF2N4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one

References

1. Janes MR, et al. Cell. 2018 Jan 25;172(3):578-589.e17.

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