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ARTS-011

Chemical Structure : ARTS-011

CAS No.: 2835520-25-5

ARTS-011 (ARTS011)

Catalog No.: PC-26072Not For Human Use, Lab Use Only.

ARTS-011 is a potent, selective, allosteric and oral inhibitor of Tyk2, selectively targeting the JH2 domain of the Tyk2 protein.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    ARTS-011 is a potent, selective, allosteric and oral inhibitor of Tyk2, selectively targeting the JH2 domain of the Tyk2 protein.

    Physicochemical Properties

    M.Wt 425.47
    Formula C20H19D3N8O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    6-(cyclopropanecarboxamido)-4-((2-methoxy-3-(3-methyl-1H-1,2,4-triazol-1-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide

    References

    1. Jin Z, et al. Br J Pharmacol. 2026 Feb 23. doi: 10.1111/bph.70338.

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