| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-38006 |
Flonoltinib maleate
|
2568842-57-7 |
Flonoltinib maleate is a potent, highly selective, dual JAK2/FLT3 inhibitor with IC50 of 0.8, 1.4, and 15 nM for JAK2, JAK2V617F, and FLT3, respectively. |
| PC-63575 |
FM-381
|
2226521-65-7 |
FM-381 (FM381) is a potent, specific, reversible and covalent inhibitor of JAK3 with IC50 of 127 pM, 400-, 2,700- and 3,600-fold selectivity over JAK1, JAK2, and Tyk2, respectively. |
| PC-61986 |
AZD 4205
|
2091134-68-6 |
Golidocitinib (AZD4205) is a potent, selective JAK1 inhibitor IC50 of 73 nM and Ki of 2.8 nM, shows high selectivity against JAK2 and JAK3 with IC50 of 13,233 nM and >30,000 nM respectively. |
| PC-61819 |
PF-06700841
|
1883299-62-4 |
PF-06700841 is a potent, selective TYK2/JAK1 kinase inhibitor that reduces IL-23 expression and directly attenuates IL-23 signaling via TYK2. |
| PC-60988 |
AS 2553627
|
1251906-07-6 |
AS 2553627 (AS2553627) is a novel potent, selective pan-JAK inhibitor with IC50 of 0.46, 0.30, 0.14 and 2.0 nM for JAK1, JAK2, JAK3 and TYK2, respectively. |
| PC-60874 |
Gingerenone A
|
128700-97-0 |
Gingerenone A is a dual inhibitor of JAK2 and S6K1 pathways, selectively kills cancer cells while exhibiting minimal toxicity toward normal cells. |
| PC-60690 |
JAK3-IN-2
|
1443235-95-7 |
JAK3-IN-2 is a potent and highly selective JAK3 inhibitor with IC50 of 0.15 nM. |
