Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-JAK/STAT Signaling-JAK

Request The Product List ofJAK JAK

Cat. No. Product Name Information
PC-24155

Milpecitinib

JAK inhibitor

Milpecitinib is potent, selective Janus tyrosine kinase (JAK) inhibitor.
PC-24148

Lirucitinib hydrochloride

JAK inhibitor

Lirucitinib hydrochloride is a potent, selective JAK inhibitor.
PC-24147

Lirucitinib

JAK inhibitor

Lirucitinib is a potent, selective JAK inhibitor.
PC-23784

Dual JAK3-TEC kinase inhibitor ZZB

JAK3/TEC kinase inhibitor

Dual JAK3-TEC kinase inhibitor ZZB is a potent, selective, covalent dual JAK3/TEC family kinases inhibitor with IC50 of 0.80 nM against JAK3 and 11.56 nM against TEC kinase interleukin-2-inducible T-cell kinase (ITK) respectively.
PC-22994

SB1578

JAK2/FLT3 inhibitor

SB1578 is a potent, selective JAK2/FLT3 inhibitor with IC50 of 46/60 nM respectively.
PC-22718

Coumermycin A1

JAK2 agonist

Coumermycin A1 (C-A1) is a small molecule JAK2 agonist that induces dimerization and activation of JAK2, also inhibits DNA Gyrase and cell division in bacteria.
PC-22634

CS12192

JAK//TBK1 inhibitor

CS12192 is a potent, selective JAK3/JAK1/TBK1 inhibitor with IC50 of 11/105/162 nM, respectively.
PC-22618

Oclacitinib maleate

JAK inhibitor

Oclacitinib (PF-03394197) maleate is a potent JAK inhibitor with IC50 of 10, 18, 99, and 84 nM for JAK1, JAK2, JAK3, and TYK2, respectively.
PC-22495

MS-1020

JAK3 inhibitor

MS-1020 is a selective, ATP-competitive small molecule JAK3 inhibitor, directly blocks JAK3 catalytic activity, potently inhibits persistently-active STAT3 in a cell type-specific manner.
PC-22202

JAK3 inhibitor RB1

JAK3 inhibitor

JAK3 inhibitor RB1 is a potent, selective and irreversible JAK3 inhibitor with IC50 of 40 nM, without inhibiting JAK1, JAK2 or TYK2 (IC50>5000 nM).
PC-21900

CEP-33779

JAK2 inhibitor

CEP-33779 is a potent, selective, and orally bioavailable inhibitor of JAK2 with IC50 of 1.3 nM, 65-fold selective over JAK-3.
PC-21596

JNJ-64251330

JAK inhibitor

Lorpucitinib (JNJ-64251330) is potent, selective and orally bioavailable pan-JAK inhibitor with IC50 of 0.37/8.6/92/7.4 nM for JAK1/JAK2/JAK3/Tyk2 respectively.

Request The Product List

* Indicates a Required FieldYour information is safe with us.

  • *Product List:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Country:
  • Additional Information:

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com