| Cat. No. |
Product Name |
Information |
| PC-73190 |
Baricitinib
JAK1/JAK2 inhibitor
|
Baricitinib (LY3009104, INCB028050) is a potent, selective and orally bioavailable JAK1/JAK2 inhibitor with IC50 of 5.9/5.7 nM, respectively. |
| PC-72038 |
NDI-031407
TYK2 inhibitor
|
NDI-031407 (NDI 031407) is a novel potent, selective TYK2 inhibitor with IC50 of 0.21 nM in radiometric assays, 20 fold selectivity over JAK3 (4.2 nM), 147 fold for JAK2 (31 nM), and 220 fold for JAK1 (46 nM). |
| PC-61277 |
EXEL-8232
|
A potent and selective, orally bioavailable JAK2 inhibitor with IC50 of 2 nM. |
| PC-45873 |
Ruxolitinib S enantiomer
|
The chirality of Ruxolitinib (INCB-018424), which is a potent, selective, orally active JAK1/JAK2 inhibitor with IC50 of 3.3/2.8 nM, respectively.. |
| PC-45817 |
Tofacitinib citrate
|
A potent, specific, orally active inhibitor of JAK3 with IC50 of 1 nM in cell-free assays. |
| PC-45875 |
Ruxolitinib sulfate
|
A potent, selective, orally active JAK1/JAK2 inhibitor with IC50 of 3.3/2.8 nM, respectively. |
| PC-45874 |
Ruxolitinib phosphate
|
A potent, selective, orally active JAK1/JAK2 inhibitor with IC50 of 3.3/2.8 nM, respectively. |
| PC-42753 |
CYT387 mesylate
|
A potent and selective JAK1/JAK2 inhibitor with IC50 of 11/18 nM. |
| PC-42752 |
CYT387 sulfate salt
|
A potent and selective JAK1/JAK2 inhibitor with IC50 of 11/18 nM. |
