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Cat. No. Product Name Information
PC-44289

BMS-911543

JAK2 inhibitor

BMS-911543 is a potent and selective small-molecule inhibitor of JAK2 with IC50 of 1.1 nM.
PC-42753

CYT387 mesylate

JAK1/2 inhibitor

Momelotinib mesylate (CYT387 mesylate) is a potent and selective JAK1/JAK2 inhibitor with IC50 of 11/18 nM.
PC-42752

CYT387 sulfate

JAK1/2 inhibitor

Momelotinib (CYT387) sulfate is a potent and selective JAK1/JAK2 inhibitor with IC50 of 11/18 nM.
PC-42751

CYT387

JAK1/2 inhibitor

Momelotinib (CYT387) is a potent and selective JAK1/JAK2 inhibitor with IC50 of 11/18 nM.
PC-45123

Itacitinib

JAK1 inhibitor

Itacitinib (INCB-039110) is a potent and selective, orally bioactive JAK1 inhibitor with IC50 of 2 nM, shows >20 fold and >200 fold selectivity over JAK2 and JAK3 respectively.
PC-26019

NS-229 hydrochloride

JAK1 inhibitor

NS-229 hydrochloride is a potent, selective JAK1 inhibitor with IC50 of 52 nM.
PC-26018

NS-229 4-methylbenzenesulfonate monohydrate

JAK1 inhibitor

NS-229 4-methylbenzenesulfonate monohydrate is a potent, selective JAK1 inhibitor with IC50 of 52 nM.
PC-25103

Voderdeucitinib

TYK2 inhibitor

Voderdeucitinib is a potent selective TYK2 inhibitor.
PC-25095

Soficitinib

TYK2 inhibitor

Soficitinib is a potent, selective tyrosine kinase 2 (TYK2) inhibitor.
PC-25094

Socrodeucitinib

TYK2 inhibitor

Socrodeucitinib is a potent, selective TYK2 inhibitor.
PC-25084

Quecitinib

JAK1/TYK2 inhibitor

Quecitinib is a potent, selective dual JAK1/TYK2 inhibitor.
PC-25063

ESK-001 hydrochloride

TYK2 inhibitor

ESK-001 hydrochloride (Envudeucitinib) is a novel allosteric, highly selective allosteric inhibitor of tyrosine kinase 2 (TYK2) with IC50 of 104-149 nM in human whole blood, binds to JH2 domain of TYK2.

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