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Cat. No. Product Name Information
PC-25103

Voderdeucitinib

TYK2 inhibitor

Voderdeucitinib is a potent selective TYK2 inhibitor.
PC-25095

Soficitinib

TYK2 inhibitor

Soficitinib is a potent, selective tyrosine kinase 2 (TYK2) inhibitor.
PC-25094

Socrodeucitinib

TYK2 inhibitor

Socrodeucitinib is a potent, selective TYK2 inhibitor.
PC-25084

Quecitinib

JAK1/TYK2 inhibitor

Quecitinib is a potent, selective dual JAK1/TYK2 inhibitor.
PC-25063

ESK-001 hydrochloride

TYK2 inhibitor

ESK-001 hydrochloride (Envudeucitinib) is a novel allosteric, highly selective allosteric inhibitor of tyrosine kinase 2 (TYK2) with IC50 of 104-149 nM in human whole blood, binds to JH2 domain of TYK2.
PC-25062

ESK-001

TYK2 inhibitor

ESK-001 (Envudeucitinib) is a novel allosteric, highly selective allosteric inhibitor of tyrosine kinase 2 (TYK2) with IC50 of 104-149 nM in human whole blood, binds to JH2 domain of TYK2.
PC-25034

TUL01101

JAK1 inhibitor

Blovacitinib (TUL01101) is a potent, selective and oral Janus kinase 1 (JAK1) inhibitor with IC50 of 3 nM, >12-fold selectivity for JAK2 and TYK2.
PC-24937

Cenacitinib

TYK2 inhibitor

Cenacitinib (VTX 958) is a potent, highly selective, allosteric and orally bioavailable inhibitor of tyrosine kinase 2 (TYK2).
PC-24735

NMS-P953

JAK2 inhibitor

NMS-P953 is a potent and selective JAK2 inhibitor with IC50 of 8 nM, displays 18-, 4- and 18-fold selective over JAK1, JAK3 and TYK2 respectively.
PC-24348

cTYK2i Compound-A

TYK2 inhibitor

cTYK2i Compound-A (Cmpd-A) is a potent, specific and brain-penetrant TYK2 inhibitor (cTYK2i) with IC50 of 6.4 nM.
PC-24191

Tofacitinib etocomil

JAK inhibitor

Tofacitinib etocomil (MH004) is a is a topical product containing a JAK inhibitor tofacitinib, shows extensive target inhibition in local skin tissues without systemic toxicities, has potential for multiple dermatologic autoimmune diseases.
PC-24170

Plodicitinib

JAK3/TEC kinase inhibitor

Plodicitinib is a highly potent, dual inhibitor of JAK3 kinase and BTK kinase with IC50 of 0.3 nM and 2.4 nM, respectively.

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