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Plodicitinib

Chemical Structure : Plodicitinib

CAS No.: 2360992-48-7

Plodicitinib

Catalog No.: PC-24170Not For Human Use, Lab Use Only.

Plodicitinib is a highly potent, dual inhibitor of JAK3 kinase and BTK kinase with IC50 of 0.3 nM and 2.4 nM, respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Plodicitinib is a highly potent, dual inhibitor of JAK3 kinase and BTK kinase with IC50 of 0.3 nM and 2.4 nM, respectively.

Physicochemical Properties

M.Wt 399.43
Formula C19H22FN7O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-[(3S,4R)-3-({2-[(1-ethyl-1H-pyrazol-4-yl)amino]-7Hpyrrolo[2,3-d]pyrimidin-4-yl}oxy)-4-fluoropiperidin-1-yl]prop-2-en-1-one

References

1. Patent WO2019132562 A1 (compound II).

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