| Cat. No. |
Product Name |
Information |
| PC-45662 |
NS-018 maleate
JAK2 inhibitor
|
NS-018 maleate (NS018, Ilginatinib) is a potent and highly selective JAK2 inhibitor (IC50=0.72 nM). |
| PC-45647 |
JAK3-IN-1
JAK3 inhibitor
|
JAK3-IN-1 is a potent and selective JAK3 inhibitor with IC50 of 4.8 nM. |
| PC-45816 |
Tofacitinib
JAK3 inhibitor
|
Tofacitinib (CP-690550) is a potent, specific, orally active inhibitor of JAK3 with IC50 of 1 nM in cell-free assays. |
| PC-42802 |
WHI-P97
JAK3 inhibitor
|
WHI-P97 is a potent, specific JAK3 inhibitor with Ki of 0.6-2.3 uM. |
| PC-42570 |
TG101209
JAK2 inhibitor
|
TG101209 (SAR-317461) is a potent, selective, orally bioavailable JAK2 inhibitor with IC50 of 6 nM. |
| PC-45875 |
Ruxolitinib sulfate
JAK1/2 inhibitor
|
Ruxolitinib sulfate (INCB-018424 sulfate, INCB18424 sulfate) potent, selective, orally active JAK1/JAK2 inhibitor with IC50 of 3.3/2.8 nM, respectively. |
| PC-45874 |
Ruxolitinib phosphate
JAK1/2 inhibitor
|
Ruxolitinib phosphate (INCB-018424 phosphate, INCB18424 phosphate) potent, selective, orally active JAK1/JAK2 inhibitor with IC50 of 3.3/2.8 nM, respectively. |
| PC-45872 |
Ruxolitinib
JAK1/2 inhibitor
|
Ruxolitinib (INCB-018424) is a potent, selective, orally active JAK1/JAK2 inhibitor with IC50 of 3.3/2.8 nM, respectively. |
| PC-42438 |
AZD-1480
JAK2 inhibitor
|
AZD-1480 (AZD1480) is a potent, selective, ATP competitive JAK2 inhibitor with Ki of 0.26 nM. |
| PC-42571 |
AZ960
JAK2 inhibitor
|
AZ960 is a potent, selective JAK2 inhibitor with Ki of 0.45 nM, IC50 of <3 nM. |
| PC-42569 |
TG-101348
JAK2 inhibitor
|
TG-101348 (Fedratinib, SAR302503) is a potent, selective JAK2 inhibitor with IC50 of 3 nM for both wt JAK2 and JAK2 V617F. |
| PC-45072 |
Solcitinib
JAK1 inhibitor
|
Solcitinib (GSK2586184, GLPG0778) is a potent, selective and orally active JAK1 inhibitor with IC50 of 9.8 nM. |
