| Cat. No. |
Product Name |
Information |
| PC-42438 |
AZD-1480
JAK2 inhibitor
|
AZD-1480 (AZD1480) is a potent, selective, ATP competitive JAK2 inhibitor with Ki of 0.26 nM. |
| PC-42571 |
AZ960
JAK2 inhibitor
|
AZ960 is a potent, selective JAK2 inhibitor with Ki of 0.45 nM, IC50 of <3 nM. |
| PC-42569 |
TG-101348
JAK2 inhibitor
|
TG-101348 (Fedratinib, SAR302503) is a potent, selective JAK2 inhibitor with IC50 of 3 nM for both wt JAK2 and JAK2 V617F. |
| PC-45072 |
Solcitinib
JAK1 inhibitor
|
Solcitinib (GSK2586184, GLPG0778) is a potent, selective and orally active JAK1 inhibitor with IC50 of 9.8 nM. |
| PC-44040 |
NVP-BSK805 dihydrochloride
JAK2 inhibitor
|
NVP-BSK805 dihydrochloride is a potent, selective and ATP-competitive inhibitor of JAK2 (V617F) and wt JAK2 (IC50=0.5 nM). |
| PC-44039 |
NVP-BSK805
JAK2 inhibitor
|
NVP-BSK805 is a potent, selective and ATP-competitive inhibitor of JAK2 (V617F) and wt JAK2 (IC50=0.5 nM). |
| PC-45575 |
CHZ-868
JAK2 inhibitor
|
CHZ-868 (CHZ868) is a potent type II JAK2 inhibitor, inhibits the proliferation of SET2 JAK2 V617F cells (GI50=59 nM). |
| PC-45448 |
Filgotinib
JAK1/2 inhibitor
|
Filgotinib (GLPG 0634) is a potent JAK1/JAK2 inhibitor with IC50 of 10 nM/28 nM in biochemical assays, less potent for JAK3 and TYK2. |
| PC-44289 |
BMS-911543
JAK2 inhibitor
|
BMS-911543 is a potent and selective small-molecule inhibitor of JAK2 with IC50 of 1.1 nM. |
| PC-42751 |
CYT387
JAK1/2 inhibitor
|
Momelotinib (CYT387) is a potent and selective JAK1/JAK2 inhibitor with IC50 of 11/18 nM. |
| PC-45123 |
Itacitinib
JAK1 inhibitor
|
Itacitinib (INCB-039110) is a potent and selective, orally bioactive JAK1 inhibitor with IC50 of 2 nM, shows >20 fold and >200 fold selectivity over JAK2 and JAK3 respectively. |
| PC-22994 |
SB1578
JAK2/FLT3 inhibitor
|
SB1578 is a potent, selective JAK2/FLT3 inhibitor with IC50 of 46/60 nM respectively. |
